R-INT improves flow-mediated dilation throughout two-hour post-exercise period in T2DM patients
THURSDAY, Sept. 29, 2016 (HealthDay News) — Resistance interval training (R-INT) is associated with improved endothelial function, especially in patients with type 2 diabetes (T2D), according to a study published online Sept. 16 in the American Journal of Physiology-Heart and Circulatory Physiology.
Monique E. Francois, from the University of British Columbia Okanagan in Canada, and colleagues examined the effect of a single session of resistance- and cardio-based INT versus a time-matched control on endothelial function in 12 age-matched patients with T2D, 12 untrained and 11 trained adults. The authors assessed flow-mediated dilation of the brachial artery at baseline, as well as immediately, one hour, and two hours after an acute bout of cardio interval training (C-INT), R-INT, and seated control (CTL).
The researchers found that in all groups, endothelial function was improved after R-INT, and the effect was most robust in T2D where flow-mediated dilation was higher immediately, one hour, and two hours after R-INT versus control (all P < 0.01). Compared with control, C-INT improved flow-mediated dilation at one-hour post-exercise (P = 0.03).
“Our data indicate a potential therapeutic effect of R-INT on endothelial function in older adults with and without T2D,” the authors write. “The mechanisms underlying these effects warrant further investigation.”
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