Treatment with corticosteroids tied to clinical and pulmonary function improvement
By Lori Solomon HealthDay Reporter
THURSDAY, Feb. 16, 2023 (HealthDay News) — Teens continued to present similarly with electronic cigarette, or vaping, product use-associated lung injury (EVALI) during the pandemic, according to a study published online Dec. 18 in Pediatric Pulmonology.
Bayan Abdallah, M.D., from the University of Texas Southwestern Medical Center in Dallas, and colleagues retrospectively evaluated electronic health records for adolescents (aged 13 to 18 years) hospitalized at one institution with EVALI. Clinical characteristics and hospital course were compared for adolescents hospitalized before and during the pandemic (19 and 22 individuals, respectively).
The researchers found that the clinical presentation of adolescents hospitalized prior to and during the COVID-19 pandemic were similar with respect to constitutional, respiratory, and gastrointestinal symptoms. Only one patient hospitalized during the pandemic had a positive severe acute respiratory syndrome coronavirus 2 real-time polymerase chain reaction test result. Among the 39 patients treated with corticosteroids, 79 percent had clinical improvement within 24 hours. Shorter median length of stay (five versus seven days) was seen for patients hospitalized during the pandemic, and they were less often discharged with home oxygen (one versus six patients). Pulmonary function tests improved from post-corticosteroid treatment to follow-up.
“Eliciting a history of vaping in adolescents presenting with constitutional, respiratory, and gastrointestinal symptoms is important to identify EVALI cases, which have continued throughout the COVID-19 pandemic,” the authors write.
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