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Monthly Archives: April 2018

Outcomes-based pricing does not reduce the costs of proprotein convertase subtilisin/kexin type 9 inhibitors

Outcomes-Based Pricing Doesn’t Cut Costs of PCSK9 Inhibitors

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Incremental cost-effectiveness ratio for PCSK9 inhibitor improved marginally in three refund scenarios
From 2015 to 2016

CDC: Overdose Deaths Up Across Drug Categories in 2015 to 2016

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Of 63,632 drug overdose deaths in 2016, 66.4 percent involved an opioid
Using CYP2C19 genotype-guided dual antiplatelet therapy selection is feasible in a real-world setting

Genotype-Guided Antiplatelet Therapy Feasible, Effective

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Genotype-guided therapy improves outcomes among CYP2C19 intermediate, poor metabolizers
In healthy women

Preconception Blood Pressure Tied to Risk of Pregnancy Loss

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Findings similar for early pregnancy blood pressure even among healthy women
For surgical inpatients aged ≥54 years

Diabetes, HbA1c Linked to Adverse Outcomes After Surgery

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DM tied to six-month mortality, major complications, ICU admission, mechanical ventilation, LOS
The majority of pharmacy customers with rhinitis select suboptimal medications

Most Patients Select Suboptimal Medications for Allergic Rhinitis

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Only 16.5 percent of customers with hay fever select optimal medications
Overweight and obesity may be contributing to specific malignancies at younger ages

Overweight, Obesity Contributing to Cancers in Young Adults

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Murine models suggest excessive weight increases cancer incidence and accelerates development
Anomalous brain development is evident among medication-naive preschoolers with attention-deficit/hyperactivity disorder

Anomalous Brain Structure ID’d in Preschoolers With ADHD

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Reductions in bilateral frontal, parietal, and temporal lobe gray matter volumes in ADHD
Alcohol consumption early in pregnancy may be a risk factor for development of gastroschisis in neonates

Early Alcohol Use in Pregnancy Tied to Gastroschisis

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No association seen with illicit, prescription, or over-the-counter drug use
Energy-based devices are both safe and effective methods of nonsurgical treatment for feminine rejuvenation

Energy-Based Devices Work Well for Feminine Rejuvenation

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Nonsurgical treatments for feminine genital rejuvenation found to be effective, well tolerated